Lumbar intervertebral discs ivds are prone to degeneration upon skeletal maturity in fact this process could explain approximately 40 of the cases of low back pain in humans despite the efficiency of pain relieving treatments the scientific community seeks to develop innovative therapeutic approaches that might limit the use of invasive surgical procedures eg spine fusion and . The lumbar intervertebral discs are the thickest compared to other spinal regions the discs are also thicker in front than the back. The intervertebral disc is a heterogeneous multicomponent structure occupying approximately 25 33 fig 1 1 of the spinal columns length 457 in the vertical position the disc confers the form of a wedge causing the convex curvature of the lumbar spine lordosis
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